Vitamin B3

Exercise +1.5 min

Blood flow/flow reserve

MACE -2.4%

Pigment/texture +MASI

Barrier/hydration -TEWL

Cognitive/neurologic improvement

Nerve protection, -2.65 TSS

Cognition/neurology improved

Ischemia reduced ~25%

NAD+ up, symptoms down

NAD+ boost; cell stress

Inflammation/oxidative stress reduced

Cancer/skin control improved

Cognitive recovery +14%

Stroke lesions -25%

Postop confusion -50%

NAD+ metabolism: +139%

Skin aging, wrinkles, spots

NAD+↑, fatigue↓

Exercise tolerance↑, fatigue↓

Early insulin +100%

Glucose iAUC -61%

Diabetes incidence -41%

UV immune protection

↓ IL-8, ↑NAD+

ALT/GGT down, fat no change

Responders +6.1%; GGT/ALP down

HDL +11–23 mg/dl

Cholesterol ↓ (lipids)

Stress system optimized

Stress resistance improved

Less arthritis impact, +29%

Better mobility, +4.5°

Phosphorus/PTH drop

Ca×P decline

↑ appetite, +weight

+B3, +B12,D