Baikal Skullcap

↓ TNF-α, cytokines

↓ plaque/bleeding, bacteria

Anxiety −2.07; sleep +27m

Depression/anxiety improved modestly

↓ inflammation, ↑ microbes

↓ plaque/bleeding, pathogens

Pain/stiffness ↓

ROM ↑

SOD/GSH-Px +23%

MDA/LPO down

Oxidative stress ↓

Inflammation ↓

ALT↓, response↑

TCRVβ7↑