Mucus clearance

Clearance: congestion↓ airflow↑

Clearance: resistance↓ patency↑

Clearance: fast onset

sputum viscosity ↓

mucus clearance ↑

+10–40%

Mucus clearance/obstruction ↓

Nasal reactivity ↓

↑ Cold-symptom clearance

↑ RTI days -47%

Nasl responsiveness ↓ 13%

Symptoms ↓ vs placebo

CARIFS −2.8

Recovery +24%

Cytokines ↓ mucus inflammation

IgM 200%